How red wine could help fight off cancer

December 9, 2014

According to the National Cancer Institute,  heavy or regular alcohol consumption increases the risk of developing esophageal cancer, particularly esophageal squamous cell carcinoma, along with a number of other cancers.  The risk of developing cancer increases with the amount of alcohol a person drinks.  While for many, a glass of red wine triggers heartburn and other effects of acid reflux disease, a new study claims that a chemical found in red wine might help reduce the risk of cancers.

 

By Jenn Gidman | Published December 08, 2014 | Newser

Overindulgence of alcohol in general may raise your risk of cancer, but a University of Colorado team explains how red wine in particular could fend that cancer off.

A study published in Advances in Experimental Medicine and Biology says that although alcohol has been linked as a risk factor for head and neck cancer, resveratrol—a chemical found in red wine and grape skins—may be able to fix cell damage caused by other [alcohol], says a release at Eureka Alert.

“Alcohol bombards your genes,” says study co-author Robert Sclafani. The body can repair some of the damage, but not all, and that’s where resveratrol comes into play.

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A glass of red wine is poured. (AP Photo/Luca Bruno)

“Cells with unrepaired DNA damage are killed [by resveratrol], so they can’t go on to cause cancer.” The mice in this experiment had cancer tumors, but when Sclafani and his group pumped the chemical compounds found in red wine into the rodents’ bodies, their tumors decreased in size and the growth of new ones was prevented, Yahoo Health reports; similar results occurred when using grape seed extract (red wine has both).

Of course, that doesn’t mean you should go on a pinot noir bender: Sclafani says that “moderation is key” and that you can also find resveratrol in nonalcoholic items such as peanuts.

Still, these findings could lead to nontoxic options in cancer treatment down the road. “Being able to counteract the pre-cancerous cells with a mild medicine would be a great alternative in treating … high-risk patients,” Sclafani tells Yahoo.

(Not everyone’s convinced about resveratrol’s powers.)

This article originally appeared on Newser: How Red Wine Helps Fight Cancer

Other source: Alcohol and Cancer RiskNational Cancer Institute,


Obama, complaining of sore throat, diagnosed with acid reflux

December 7, 2014

(Reuters) – President Barack Obama, who had medical tests on Saturday after complaining of a sore throat, is suffering from acid reflux, the president’s physician said.

“The president’s symptoms are consistent with soft tissue inflammation related to acid reflux and will be treated accordingly,” Obama’s doctor, Captain Ronny Jackson, said in a statement.

Acid reflux is a condition in which the stomach contents flow back up from the stomach into the esophagus, causing such symptoms as heartburn and sore throat.

Obama, 53, went to Walter Reed military hospital for a fiber optic exam of his throat and since swelling was detected, doctors decided to perform a CT scan as well, Jackson said.

“The CT scan was conducted this afternoon purely as a matter of convenience for the President’s schedule. The CT scan was normal,” Jackson added.

Jackson said he recommended Obama go to Walter Reed for the tests after the president complained of suffering from a sore throat over the past couple of weeks.

Jackson did not give any cause for Obama’s case of the illness. There are many risk factors for acid reflux, including smoking, use of alcohol and hiatal hernia, according to the U.S. National Library of Medicine. Most people respond to lifestyle changes and medicines, although many patients need to continue on medication to control their symptoms.

Click here to read the full article "Obama, complaining of sore throat, diagnosed with acid reflux" on Reuters.com.

Acid reflux disease, also known as Gastroesophageal Reflux Disease or GERD, is one of the primary risk factors associated with esophageal cancer, the fastest growing cancer in the United States, according to the National Cancer Institute.

It is imperative that people who suffer from heartburn more than twice weekly speak to their doctor.   There are no routine or standard screening tests for esophageal cancer.  Unfortunately, symptoms, such as difficulty swallowing or food getting stuck, typically appear once the cancer has advanced and becomes difficult to treat.

Chronic and severe acid reflux can significantly damage the esophagus.  Not only can it increase the risk of esophageal cancer, but it can lead to other serious health problems, such as ulcers, bleeding and scarring.

Lifestyle changes can help to reduce GERD symptoms.  Click here for some tips to control your acid reflux.

Some medications help to temporarily alleviate GERD symptoms.  However, these medications are typically not intended to be taken for an extended periods of time.  Remember to read the label on these medications and consider the side effects.

Some patients may be candidates for nonsurgical, less invasive options to treat GERD.

As advocates for esophageal health and the prevention of esophageal cancer, we urge everyone suffering from chronic heartburn to consult a medical professional.  Talk to your doctor about your symptoms and options.

 


Support Esophageal Cancer Awareness This #GivingTuesday

December 2, 2014

giving tuesday periwinkle esophageal cancer the salgi esophageal cancer research foundation

Today is Giving Tuesday! The Salgi Esophageal Cancer Research Foundation is honored to participate in this third annual event.  In 2012, a group of nonprofit professionals decided to create an annual day of giving.  They positioned it around the biggest days of consuming, Black Friday and Cyber Monday. Giving Tuesday opens the giving season and with your help, we will raise funds to spread awareness, encourage early detection and support research of esophageal cancer…in hopes of a cure.™  

How can you help make Giving Tuesday a success?

  • Help us get the word out on social media by visiting and liking our pages: Facebook, Twitter and Instagram;
  • Consider a donation: SALGI.org/donate, as a 501(c)(3) charity, all donations are tax-deductible;
  • Share photos of your loved ones who have been affected by esophageal cancer on social media. Tag us in the photos and we’ll re-post them on our pages;
  • Invite your co-workers, family members and friends to contribute by using the message below via social media or email:

 

I am supporting The Salgi Esophageal Cancer Research Foundation today on Giving Tuesday and I hope you will, too!  [Optional: Insert personal story/reason for helping.]  Did you know esophageal cancer is the fastest growing cancer in the US, according to the National Cancer Institute? You can support awareness and research efforts by making a tax-deductible donating online: SALGI.org/donate, and by sharing this information with your friends, family and colleagues by email or on Facebook and/or Twitter.  Thank you in advance!

 

Giving Tuesday helps to unite us in the spirit of giving and to bring a spotlight to esophageal cancer, a cause that needs desperate attention.  Let’s make this Giving Tuesday a great success! Thank you in advance for helping to make a difference today and every day.


Thanksgiving Tips to manage GERD

November 26, 2014

The holidays are a wonderful time of year when family and friends can gather together, share thanks and enjoy an abundant feast filled with our favorite foods.  Certain habits can cause some unwanted holiday heartburn.  Learn how to enjoy the holidays and all of the delicious foods while managing your acid reflux symptoms.

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Here are a few tips for you to take with you to the Thanksgiving dinner table:

  1. Limit beverage consumption while eating.  Sometimes fluids, especially carbonated beverages, can cause more gas in the stomach when combined with food intake. Try to drink slowly after you are done eating.

 

  1. Monitor what you are eating and avoid foods that trigger acid reflux.  Foods that have the worse effects on acid reflux are spicy, fatty, fried and citrus foods. Food and drinks that trigger GERD symptoms vary from person to person, so it is important to know your body and determine which are best for you.

 

  1. Limit or avoid alcohol.  There are some people, however, who should avoid all alcohol consumption, as even the smallest amounts can cause acid reflux. Alcohol increases the production of stomach acids. Alcohol also relaxes the lower esophageal sphincter (LES), the muscle that is in charge of keeping stomach contents from refluxing into the esophagus.

 

  1. Don’t over-eat.  Ask for a smaller plate, take a small sample from each dish and choose “safe” foods that you’ve predetermined do not flare up your acid reflux symptoms. When you’re feeling tempted to overindulge, ask yourself “Is having that second helping of pumpkin pie worth the hours of pain and misery due to the acid reflux afterwards?”

 

  1. Chew slowly. Help your digestive system by chewing every bite slowly and thoroughly. Put your fork down in between bites to help remind yourself to go slow while eating.

 

  1. Wear loose clothing. Clothing which is tight especially around the mid-section can put extra pressure on the abdomen and increase acid reflux symptoms.

 

  1. Sit upright for several hours after you’ve eaten. Or better yet, take a leisurely family stroll around the neighborhood to help settle your stomach and aid digestion. Avoid any rigorous exercise, as it can upset the digestion process and cause reflux symptoms.

 

  1. Pass on the after-dinner coffee.  For some, coffee can increase acid reflux and cause symptoms to flare up.  Both caffeinated and decaffeinated coffee have shown to aggravate GERD symptoms.

 

  1. Ditch all tobacco products.  Tobacco, including cigarettes, cigars, chewing tobacco and pipe tobacco not only worsens GERD symptoms, but it can cause people to develop GERD.   Like alcohol, tobacco weakens the lower esophageal sphincter (LES) and increases stomach acids.

 

 

While occasional heartburn is not typically a cause for concern, as billions of Americans experience heartburn at some point in their lives, heartburn that occurs more than twice weekly should not be taken lightly, as it could be an indicator of GERD.  GERD stands for Gastroesophageal Reflux Disease which is a disease of the digestive system.

 

Also known as acid reflux disease, GERD is a progressive disease, which means that it worsens overtime, especially if it is not properly treated.  The reflux of acids from the stomach damages the lining of the esophagus and can cause major health problems, including an increased risk of esophageal cancer. Speak to your doctor if you are experiencing frequent or chronic heartburn or if your acid reflux symptoms are worsening.

If you, or someone you know, has GERD, RefluxMD has put together an eBook that is surely a must-read!  To download a FREE copy of I Have GERD, Now What?”, click here.

 

From all of your friends at The Salgi Esophageal Cancer Research Foundation, we wish you a happy, healthy and heartburn-free Thanksgiving!

 

 

 

Sources:

 

 


Make a Difference This Holiday Season

November 26, 2014

As the holiday season approaches, you are getting ready to spend time with loved ones, exchange gifts and celebrate the season and all of its joys. It is also a wonderful time of year to share our important mission with everyone that you know. We at The Salgi Esophageal Cancer Research Foundation understand how valuable your time is; especially during the next few months. Here are a few simple yet powerful ways to take a stand against esophageal cancer during the holidays.

GERD Awareness Week

During your Thanksgiving preparations and feast, take time to spread the message regarding the dangerous link between chronic heartburn and esophageal cancer.  GERD Awareness Week occurs annually on the week of Thanksgiving.  This year GERD Awareness Week starts on Sunday November 23 and ends on Saturday November 29th.

While it is tempting to indulge in our favorite holiday foods and then sometimes even experience a little heartburn, it is certainly a cause for concern if heartburn occurs more than what doctors consider normal, which is twice a week or more. You might be surprised how many people still do not know of the dangers associated with chronic heartburn, also known as GERD or acid reflux disease. Remember, chronic heartburn that is not properly treated can increase the risk of esophageal cancer.  Learn more about GERD and what you can do to promote this important week on our “GERD Week” page.

 

Memorial and Tribute Gifts

During this season of joy, we ask that you remember us and consider a memorial or tribute donation as a gift to your loved ones. Your donations go directly to our mission of raising awareness, encouraging early detection and funding research of esophageal cancer in hopes of a cure. The Salgi Esophageal Cancer Research Foundation will send a letter of acknowledgement to your loved one, notifying them of your gift donation.  To make a memorial or tribute donation, click here.

 

AmazonSmile

When you shop AmazonSmile, Amazon will make a donation to our charity each time a purchase is made. This is one of the most effortless ways to give back during the holiday season.  Skip the chaos and crowds on Black Friday, shop online in the convenience of your own home all while supporting this mission. Don’t forget Cyber Monday! AmazonSmile will have even more deals for the holidays on Monday, December 1, 2014, to help you raise even more for esophageal cancer research without spending any extra money. Encourage everyone you know to shop AmazonSmile and select us as your charity to support. AmazonSmile can be done year-round, too. Use this link each and every time you shop on Amazon. Click here!

 

#GivingTuesday

Giving Tuesday is a global day dedicated to giving back. This year, on Tuesday, December 2, 2014, you can join us and together we can celebrate this day in honor of everyone who has been affected by esophageal cancer. Encourage everyone you know to make a donation using this link: SALGI.org/donate. Use the hashtag #GivingTuesday along with #EsophagealCancer on social media and tag us in your posts on Facebook, Twitter, Instagram and Pinterest.

Connect with us using the buttons below and share this life-saving mission with everyone you know!

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Proton Pump Inhibitors Decrease Diversity in Gut Microbiome, Increase Risk for Complications

November 26, 2014

Before reaching for that daily antacid, you might consider what it’s doing to the trillions of bugs living in your gut. A new Mayo Clinic study in the open access journal Microbiome shows that people who regularly take proton pump inhibitors (PPIs) have less diversity among their gut bacteria, putting them at increased risk for infections like clostridium difficile and pneumonia, in addition to vitamin deficiencies and bone fractures.

“Evidence has been mounting for years that long-term use of proton pump inhibitors poses increased risks for a variety of associated complications, but we have never really understood why,” says John DiBaise, M.D., a Mayo Clinic gastroenterologist and senior author on the study. “What this study does for the first time is demonstrate a plausible explanation for these associated conditions.”

The gut microbiome consists of trillions of bacteria. Rather than causing disease, most of these bacteria are friendly and aid in everything from digestion and vitamin synthesis to immune system regulation and possibly, mood stabilization.

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Diet, genetics and environmental exposure all play a role in maintaining a healthy microbiome, which is critical to overall wellness, says Dr. DiBaise. Significant changes to the microbiome, like those caused by proton pump inhibitors, can put people at risk for over-colonization by such undesirable species as clostridium difficile, he says.

Proton pump inhibitors are primarily used to treat ulcers and acid reflux, and include the generic names omeprazole, pantoprazole, esomeprazole, lansoprazole, rabeprazole and dexlansoprazole.

Many epidemiological studies have linked PPIs to nutritional, metabolic and infectious disorders, despite the class of drugs’ long history of safety and efficacy. Specifically, their prolonged use has been associated with iron and vitamin B12 deficiencies, hypomagnesemia, osteoporosis-related fractures, small intestinal bacterial overgrowth, and community-acquired pneumonia. The Food and Drug Administration has issued several safety communications about use of high-dose PPIs (available through prescription) and long-term use at any dose, including over-the-counter medications.

Safety implications of the study have yet to be determined, and patients should consult a qualified medical professional before changing any drug regimen, says Dr. DiBaise.

“We’re not saying people should stop taking their regular antacids; despite the many health risks associated with PPI use, they have an extensive track record of safety when used as directed,” Dr. DiBaise says. “What we are saying is that the medical and research communities should consider these medications in the context of the patient’s microbiome. This is an area that needs further study.”

In patients with mild reflux symptoms, lifestyle changes may be sufficient to curb discomfort, Dr. DiBaise says. Non-pharmacological methods to control acid reflux include:

  • Eat smaller portions at meals
  • Consume less fat
  • Avoid laying down for at least 2 hours after eating (avoid late-night snacks)
  • Wear loose fitting clothing
  • Elevate the head of the bed about 6 inches (this is best done by placing a block under the headboard, rather than stacking pillows)
  • Lose weight (as little as 5 to 10 pounds may help)
  • Avoid alcohol, tobacco and foods that trigger symptoms

Daily medications become necessary in those whose reflux symptoms persist and impair their quality of life despite these lifestyle modifications, says Dr. DiBaise. Whether less potent acid inhibitors like histamine H2 antagonists, cause similar changes to the microbiome is unknown.

Coauthors of the study are Charlie Seto of the University of Minnesota, and Patricio Jeraldo, Ph.D., Robert Orenstein, D.O., and Nicholas Chia, Ph.D., all of Mayo Clinic.

The study was funded by the Mayo Clinic Center for Individualized Medicine and the Minnesota Partnership for Biotechnology and Medical Genomics. Dr. Jeraldo received funding for this project from the University of Illinois at Urbana-Champaign.

 

The above story is based on materials provided by Mayo Clinic. The original article was written by Sam Smith.

References:

Charlie T Seto, Patricio Jeraldo, Robert Orenstein, Nicholas Chia, John K DiBaise.Prolonged use of a proton pump inhibitor reduces microbial diversity: implications for Clostridium difficile susceptibility. Microbiome, 2014; 2 (1): 42 DOI: 10.1186/2049-2618-2-42
 
Mayo Clinic. “Proton pump inhibitors decrease diversity in gut microbiome, increase risk for complications.” ScienceDaily. ScienceDaily, 25 November 2014. www.sciencedaily.com/releases/2014/11/141125074656.htm

Most Common Heartburn Triggers

November 25, 2014

As GERD Awareness week continues, we’ve put together a list of the most common food and drinks that the majority of people say triggers their heartburn, the most common symptom of acid reflux disease.   Food and drinks that trigger acid reflux symptoms vary from person to person, so it is important to manage your diet according to the foods and drink that trigger your symptoms.

Please remember to always speak to your doctor if you have any concerns about your health especially if you are experiencing frequent heartburn.  Heartburn which occurs more than twice a week may indicate GERD and if not properly treated can cause damage to the lining of the esophagus and can also increase the risk of esophageal cancer.

Most Common Heartburn Triggers:

-Alcohol.
-Spicy foods.
-Fatty and fried foods.
-Tomatoes and tomato sauce.
-Chocolate.
-Peppermint.
-Citrus fruits and juices.
-Coffee and caffeinated drinks.

Click here to get a free copy of the eBook: I Have GERD, Now What?” provided by

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