The Salgi Esophageal Cancer Research Foundation believes that educating as many people as possible regarding risk factors, possible warning symptoms, and statistics associated with esophageal cancer will help in the fight to improve early detection and survival.
Fast Facts
-Esophageal cancer has increased over 733% in the past four decades and is considered the fastest growing cancer in the US and western world.
-Risk factors include:
- Gastroesophageal Reflux Disease (GERD, acid reflux, chronic heartburn),
- obesity,
- poor nutrition,
- tobacco use,
- excessive alcohol use,
- Barrett’s esophagus.
-As one of the deadliest cancers, esophageal cancer has a 5-year survival rate of only 21.6%.
-There are no routine or standard screenings to improve early detection of esophageal cancer.
-Symptoms often arise late once the cancer is considered advanced or “distant” (spread to lymph nodes and other organs.)
-Stage IV esophageal cancer has a survival rate of only 5.6%.
-Despite all these facts, esophageal cancer research is extremely underfunded.
-In 2025, an estimated 22,070 will be diagnosed and there will be an estimated 16,250 deaths.
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The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) nonprofit organization as recognized by the Internal Revenue Service.
Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Sources:
Esophageal Cancer Sees Dramatic Spike.” Gastroenterology and Endoscopy News. https://www.gastroendonews.com/Inthe-News/Article/10-18/Esophageal-Cancer-Sees-Dramatic-Spike-/53083
Management of Barrett’s oesophagus and intramucosal oesophageal cancer: a review of recent development. Shanmugarajah Rajendra and Prateek Sharma, Copyright, 2012, National Center for Biotechnology Information, U.S. National Library of Medicine. Bethesda MD, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437535
SEER Cancer Statistics Factsheets: Esophageal Cancer. National Cancer Institute. Bethesda, MD, 2025 http://seer.cancer.gov/statfacts/html/esoph.html
Survival rates for cancer of the esophagus by stage. 2025, American Cancer Society, Atlanta, GA, http://www.cancer.org/cancer/esophaguscancer/detailedguide/esophagus-cancer-survival-rates
Barrett’s esophagus and esophageal adenocarcinoma in adults: long-term GERD or something else? Pondugula K, Wani S, Sharma P, Copyright, 2007 National Center for Biotechnology Information, U.S. National Library of Medicine. Bethesda, MD, http://www.ncbi.nlm.nih.gov/pubmed/18377797
A Snapshot of Esophageal Cancer Trends in NCI Funding for Esophageal Cancer Research. 2025, National Cancer Institute, Bethesda, MD, http://www.cancer.gov/researchandfunding/snapshots/pdf/Esophageal-Snapshot.pdf
Non-Invasive Detection of Esophageal Cancer using Genetic Changes in Circulating Cell-Free DNA Avicenna Journal of Medical Biotechnology, Vol. 4, No. 1, January-March 2012 http://www.ajmb.org/PDF/En/FullText/76.pdf
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