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Esophageal cancer (adenocarcinoma) has increased over 600% in the past decades; making it the fastest growing cancer in the United States, according to the National Cancer Institute.*

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Latest Incidence and Mortality of Esophageal Cancer in the United States:

In 2017, an estimated 16,940 will be diagnosed with esophageal cancer and there will be an estimated 15,690 deaths from esophageal cancer.¹

Only 18.4% of patients diagnosed with esophageal cancer will survive 5(+) years.

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Based on data from SEER 18 2006-2012. Gray figures represent those who have died from esophageal cancer. Periwinkle figures represent those who have survived 5 years or more. seer.cancer.gov

Incidence and Mortality of Esophageal Cancer in the United States (1999-2016):

Year     Incidence (Diagnosis)       Mortality (Deaths)
2016 16,910 15,690
2015 16,980 15,590
2014 18,170 15,450
2013 17,990 15,210
2012 17,460 15,070
2011 15,914 14,446
2010 15,813 14,490
2009 16,487 13,908
2008 16,299 13,714
2007 15,706 13,592
2006 15,664 13,685
2005 15,228 13,499
2004 15,299 13,023
2003 14,419 12,860
2002 13,260 12,700
2001 13,031 12,529
2000 13,051 12,232
1999 12,532 11,917

Notes: Incidence counts cover approximately between 91%-99% of the U.S. population; death counts cover 100% of the U.S. population. Use caution when comparing incidence and death counts.

Percent of Esophageal Cancer Cases By Stage:

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  • Localized (20%)
    Confined to Primary Site
  • Regional (31%)
    Spread to Regional Lymph Nodes
  • Distant (38%)
    Cancer Has Metastasized
  • Unknown (11%)
    Unstaged

Esophageal Cancer 5-Year Survival Rates By Stage:

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  • Localized (41.3%)
    Confined to Primary Site
  • Regional (22.8%)
    Spread to Regional Lymph Nodes
  • Distant (4.5%)
    Cancer Has Metastasized
  • Unknown (12.48%)
    Unstaged
  • Percent of Esophageal Cancer Patients Surviving Five Years: (18.4%)

 

 

 

Esophageal Cancer Research Funding:

 

Source: NCI Office of Budget and Finance.

Source: NCI Office of Budget and Finance.

 
Despite its rapid increase and poor prognosis, esophageal cancer research receives little private and/or government funding.
 
The National Cancer Institute decreased its investment in research of esophageal cancer by 15% in 2012. In 2013, esophageal cancer research funding was again decreased.  The National Cancer Institute invested only $26.5 million for esophageal cancer research out of their total $4.79 billion budget, in 2013.   Then, in 2014, The National Cancer Institute increased their funding.  The NCI spent $28.4 million for esophageal cancer research out of their total budget.  
 
The American Cancer Society reports that they fund a total of 782 cancer research grants.  Unfortunately, only 8 of these are for esophageal cancer research. (As of August 1, 2016)
 
Cost of Esophageal Cancer Care
 
$1.6 billion dollars was estimated to be spent on esophageal cancer treatment alone during 2016 in the U.S. (Source: Cancer.gov)
 
 

Age-Adjusted Death and Incidence Rates by State:

Age-adjusted incidence rates by State, All Races, Both Sexes for Esophageal Cancer.

Age-adjusted incidence rates by State, All Races, Both Sexes for Esophageal Cancer.

 
 
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Age-adjusted death rates by State, All Races, Both Sexes for Esophageal Cancer.

 
 

 
 
Sources:
Department of Health and Human Services, Centers for Disease Control and Prevention,cdc.gov 
National Cancer Institute, Surveillance, Epidemiology and End Results Program, seer.cancer.gov 
American Cancer Society, Cancer Facts & Figures, 2012-2015, cancer.org
Management of Barrett’s oesophagus and intramucosal oesophageal cancer: a review of recent development, nlm.nih.gov 
Esophageal Cancer On The Rise, webmd.com
National Cancer Institute: PDQ® Esophageal Cancer Treatment. Bethesda, MD: National Cancer Institute. cancer.gov
National Cancer Institute: A Snapshot of Esophageal Cancer. cancer.gov
American Cancer Society, Explore Research, cancer.org
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