September 14, 2015
Article via Oncologynurseadvisor.com | September 11, 2015
“A nurse-led walk-and-eat intervention is feasible and effective to preserve functional walking capacity and nutritional status in patients with esophageal cancer undergoing neoadjuvant chemoradiotherapy, according to a recent study published in the journal The Oncologist.
For the study, researchers at National Taiwan University in Taipei, Taiwan, sought to evaluate the impact of a walk-and-eat intervention in patients with locally advanced esophageal cancer stage 2B or higher receiving neoadjuvant chemotherapy and radiation. A total of 59 participants were randomly assigned to receive the intervention, which involved nurse-supervised walking 3 times per week and weekly nutritional advice, or usual care during 4 to 5 weeks of chemoradiotherapy.
Results showed that those who received the intervention had a 100-meter less decline in walk distance than control patients, 3-kg less decrease in hand-grip strength, and 2.7-kg less reduction in body weight. Researchers found that the patients’ age did not impact these endpoints.
The study also demonstrated that patients that received the walk-and-eat intervention had significantly lower rates of need for intravenous nutritional support and wheelchair use.”
Read the full article: http://www.oncologynurseadvisor.com
The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) non profit organization as recognized by the Internal Revenue Service.
Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
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Posted by salgiblogs
July 28, 2015
The Salgi Esophageal Cancer Research Foundation has issued its first round of funding for esophageal cancer research earlier this month.
The foundation awarded program director, Dr. Carlos Minacapelli and Rutgers Robert Wood Johnston Medical School grant funding.
In 2011, The Salgi Esophageal Cancer Research Foundation was established to raise awareness, encourage early detection and to fund research of esophageal cancer. Since 2011, the foundation has both raised awareness and encouraged the importance of earliest possible detection throughout New England, across the United States and internationally.
“The Salgi Esophageal Cancer Research Foundation is excited to be a part of Dr. Minacapelli’s and Rutger’s research efforts in honor of all the brave men and women who were affected by esophageal cancer and to hopefully reduce incidence and improve outcomes for individuals in the future” President of the foundation stated.
The Salgi Esophageal Cancer Research Foundation would like to thank all of our supporters and donors who believe in this mission and who make these accomplishments possible. However, this is just the beginning. We received many other research requests that we were unable to fund at this time. We need to continue our efforts to fundraise so that we may continue to fund research.
Gastroesophageal Reflux Disease, also known as GERD or acid reflux disease, of which the most common symptom is chronic heartburn, is one of the primary risk factors associated with esophageal cancer. Other risk factors include obesity, poor nutrition and smoking. With over a 600% increase in the past decades, esophageal cancer is among the fastest growing and deadliest cancers in the United States and western world.
Currently, there are no standard or routine screenings to detect esophageal cancer in earlier stages. Symptoms, such as difficulty swallowing, typically appear once the cancer has become advanced and the overall five-year survival rate is only 17.5%. Despite its rapid increase and poor prognosis, esophageal cancer receives very little awareness and research funding.
To make a tax-deductible donation to The Salgi Esophageal Cancer Research Foundation, please visit: SALGI.org/donate.
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Posted by salgiblogs
July 10, 2015
“Cancer Research UK scientists have found that ‘jumping genes’ may add to the genetic chaos behind more than three-quarters of esophageal cancer cases, according to research published in BMC Genomics.
The scientists, from the University of Cambridge, used cutting-edge technology that can read DNA to study the genes of 43 esophageal tumour and blood samples to discover how much these mobile genetic sequences travel.
‘Jumping genes’, called L1 elements, can uproot themselves and move to new areas in the DNA, sometimes accidentally moving into genes that control the cell’s growth.
They found evidence that this happened around 100 times in each tumour sample, and in some tumours it happened 700 times.
If a jumping gene lands in or near an important gene that controls cell growth, it can wreak havoc, changing how the gene works so that it inadvertently tells the cell to grow and divide out of control – which could lead to cancer.
Study author Dr Paul Edwards, at the Cancer Research UK Cambridge Institute, said: “These jumping genes play hopscotch across our genetic code in cancer cells more than in normal cells. When one of these mobile genetic sequences plants itself in the middle of a gene that controls the cell’s growth it radically alters how the cell behaves, which can sometimes cause cancer.
“Research has shown that this might also happen in lung and bowel cancers. So it’s vital we find out more about how the cells do this in a bid to find ways to treat these cancers.”
The research is part of the International Cancer Genome Consortium (ICGC) – a global project using the latest gene sequencing technology to reveal the genetic changes behind cancer. The esophageal cancer project is funded by Cancer Research UK.
Dr Kat Arney, Cancer Research UK’s science information manager, said: “Esophageal cancer is one of the hardest cancers to treat, and we are committed to funding more research to find out its underlying causes. These new findings reveal more about the genetic chaos that underpins esophageal tumours, and could one day help us develop better ways to diagnose, treat and monitor the disease.”
References: Paterson et al. Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired end sequencing analysis. BMC Genomics. DOI: 10.1186/s12864-015-1685-z.
This post is based on materials provided by Cancer Research UK.
The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) non profit organization as recognized by the Internal Revenue Service.
Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
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Posted by salgiblogs
March 26, 2015
By Liz Janetschek | The ASCO Post. March 25, 2015, Volume 6, Issue 5
The information contained in this Clinical Trials Resource Guide includes actively recruiting observational, interventional, phase I, phase II, and phase III clinical studies for patients with newly diagnosed or recurrent esophageal cancer. All of the studies are listed on the National Institutes of Health website at ClinicalTrials.gov.
Read the full article, “Clinical Trials Actively Recruiting Patients With Esophageal Cancer,” The ASCO Post.
The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) non profit organization as recognized by the Internal Revenue Service.
Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Leave a Comment » | The Salgi Foundation - Esophageal Cancer Awareness, Early Detection & Research | Tagged: acid, acid reflux, acid reflux disease, acid reflux drugs, acid reflux medication, awareness, barrett's, barrett's esophagus, cancer, cancer awareness, cancer charity, cancer of the esophagus, cancer run, cancer walk, charity, clinical trials, diet, disease, drugs, esophageal, esophageal cancer, esophageal cancer awareness, esophageal cancer charity, esophageal cancer research, esophageal cancer research charity, esophagus, exercise, fit, fitness, food, gastroenterology, Gastroesophageal Reflux Disease, gerd, GI health, GI news, GI research, health, health news, healthy., heartburn, heartburn medication, heartburn sufferer, heartburn symptoms, lifestyle, medication, news, nonprofit, nutrition, obesity, ppi, reflux disease, research news, rhode island, ri, silent reflux | Permalink
Posted by salgiblogs
February 7, 2012
One way to treat gastroesophageal reflux disease (GERD) is through changes in diet and nutrition. Of course, this approach must be discussed with your doctor before attempting to put into place on your own. While making changes in your diet may be extremely helpful for some it can also be challenging. Many are not sure what foods are “safe” to eat and end up wandering aimlessly in the grocery store on their shopping trips.
Below is a list that we have put together of foods which have been shown to be suitable for GERD sufferers. The best practice is to “test” certain foods and see how your body reacts to them. Everyone will react differently to different foods. Keeping a food journal with details of what you’ve had to eat or drink can help you keep track of what affects your reflux. Write down everything that you’ve had to eat or drink along with what time of the day and if you’ve had any symptoms from the food or drink.
When grocery shopping, consider the size of the item you are buying. Another easy way to reduce your acid reflux or GERD is to reduce portion sizes. Eating smaller meals has proven to reduce episodes of GERD.
GERD Grocery Shopping List
Apple- juice, dried or fresh
Banana
Pears
Potato
Broccoli
Cabbage
Carrots
Celery
Corn
Beans
Lentils
Mushrooms
Parsnips
Peas
Spinach
Kale
Squash
Green beans
Brown Rice
Multi-grain or whole wheat bread
Bran Cereal
Oatmeal
Corn Bread
Graham Crackers
Pretzels
Rice cakes
Feta cheese
Goat cheese
Fat-free cream cheese
Fat-free sour cream
Low-fat soy cheese
Skim milk
Egg substitute
Egg whites
Skinless chicken breast
Extra lean steak
Extra lean ground beef
Salmon
Fish – no added fat
Ginger
Honey
Basil
Cilantro
Chamomile tea
As always, consult your doctor before making any lifestyle changes.
These suggestions are for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
Sources:
Magee, Elaine. “Heartburn: Foods to Avoid.” WebMD, WebMD, http://www.webmd.com/heartburn-gerd/features/heartburn-foods-to-avoid#1.
Johnson, Jon. “Diet Tips for GERD: Foods to Eat and Avoid.” Medical News Today, MediLexicon International, http://www.medicalnewstoday.com/articles/314690.php.
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Posted by salgiblogs
The Salgi Esophageal Cancer Research Foundation 