April is Esophageal Cancer Awareness Month

April 1, 2025

It’s here!  April is Esophageal Cancer Awareness Month.  

The Salgi Esophageal Cancer Research Foundation is hard at work, and we need your help to make a BIG impact!

Join us as we raise awareness, encourage early detection and fund research of esophageal cancer…in hopes of a CURE™!

Esophageal cancer is one of the fastest growing and deadliest cancers in the United States, United Kingdom and other western countries.

The Salgi Esophageal Cancer Research Foundation awarded two research grants, the first in 2015 and the second in 2018.   The research awarded in 2018, a breath test for esophageal cancer, is currently underway.   

Then in 2023, The Salgi Esophageal Cancer Research Foundation awarded THREE grants for esophageal cancer research. 

We are honored to share that this year, The Salgi Esophageal Cancer Research Foundation has opened our grant funding program again.

All grants are awarded in honor of all who have been affected by esophageal cancer. 

While these are tremendous accomplishments, esophageal cancer research is critically underfunded and medical researchers continuously inquire about funding.  We are looking forward to awarding MORE funding for esophageal cancer research!

In addition, due to lack of awareness and no routine or standard screenings, many individuals typically face advanced prognosis with limited treatment options. 

Now, more than ever, your support is critically needed to enable this charity to fulfill our mission.

When you make a donation to our charity you are directly supporting esophageal cancer awareness, early detection and research. All donations can be made as a one-time donation or can be recurring, are tax-deductible and go to our mission!

Make an even bigger impact! Create your own custom, fundraising page!

Click the “fundraise” button below to get started. 

Learn the Facts

-Esophageal cancer increased 733% in the past four decades.

-Esophageal cancer is one of the fastest growing cancers in the United States and western world.

-Esophageal cancer has an overall 5-year survival rate of only 21.6%.

-There are no routine or standard screenings.

-Symptoms often arise late, once the cancer has spread.

-Stage IV has a survival rate of 5.3%.

-Esophageal cancer research is critically underfunded.

-In 2016, an estimated $1.6 billion was spent on esophageal cancer care in the United States.

-2025 estimates for esophageal cancer: 22,070 diagnoses & 16,250 deaths.

2025 Infographic

Save the infographic below and share it on social media to raise awareness.
Tag us in your posts. @SalgiFoundation

The Salgi Esophageal Cancer Research Foundation is a registered 501(c)3 organization.  EIN: 45-3633809.

Join us on social media!

Follow, like, share and connect with us on social media!

Facebook.com/SalgiFoundation
Twitter.com/SalgiFoundation
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April is Esophageal Cancer Awareness Month

April 5, 2024

The month of April is dedicated to this life-saving mission. Even though The Salgi Esophageal Cancer Research Foundation is hard at work, year-round, April is a special time to come together to make a difference!

Join us this month as we continue to raise awareness, encourage early detection and fund research of esophageal cancer…in hopes of a CURE™!

Esophageal cancer is one of the fastest and deadliest cancers in the United States, United Kingdom and other western countries.

The Salgi Esophageal Cancer Research Foundation awarded two research grants, the first in 2015 and the second in 2018. The research awarded in 2018, a breath test for esophageal cancer, is currently underway.

We are honored to share that in 2023, The Salgi Esophageal Cancer Research Foundation awarded THREE grants for esophageal cancer research. All grants are awarded in honor of all who have been affected by esophageal cancer.

While these are tremendous accomplishments, esophageal cancer research is critically underfunded and medical researchers continuously inquire about funding. We are working to fund MORE worthy research for esophageal cancer!

In addition, due to lack of awareness and no routine or standard screenings, many individuals typically face advanced prognosis with limited treatment options.

Now more than ever your support is critically needed to enable this charity to fulfill our mission.

When you make a donation to our charity you are directly supporting esophageal cancer awareness, early detection and research. Donations can be made one-time or recurring, are tax-deductible and go to our mission!

Make an even bigger impact! Create your own custom, fundraising page. Click the “fundraise” button below to get started.

Learn the Facts

-Esophageal cancer increased 733% in the past four decades.

-Esophageal cancer is one of the fastest growing cancers in the United States and western world.

-Esophageal cancer has an overall 5-year survival rate of only 21.7%.

-There are no routine or standard screenings.

-Symptoms often arise late, once the cancer has spread.

-Stage IV has a survival rate of 5.6%.

-Esophageal cancer research is critically underfunded.

-In 2016, an estimated $1.6 billion was spent on esophageal cancer care in the United States.

-2024 estimates for esophageal cancer: 22,370 diagnoses & 16,130 deaths.

2024 Infographic

Save the infographic below and share it on social media to raise awareness.
Tag us in your posts. @SalgiFoundation

The Salgi Esophageal Cancer Research Foundation

The Salgi Esophageal Cancer Research Foundation is a registered 501(c)3 organization. EIN: 45-3633809.

Facebook.com/SalgiFoundation

Instagram.com/SalgiFoundation

YouTube.com/SalgiFoundation

Twitter.com/SalgiFoundation

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University of Louisville researchers find association between oral bacteria and esophageal cancer (ECSS)

March 3, 2016

Via: Kyforward.com

Louisville, KY– “University of Louisville School of Dentistry researchers have found a bacterial species responsible for gum disease, Porphyromonas gingivalis, is present in 61 percent of patients with esophageal squamous cell carcinoma (ESCC).

The findings, published recently in Infectious Agents and Cancer, only detected P. gingivalis in 12 percent of tissues adjacent to the cancerous cells, while this organism was undetected in normal esophageal tissue.

“These findings provide the first direct evidence that P. gingivalis infection could be a novel risk factor for ESCC, and may also serve as a prognostic biomarker for this type of cancer,” said Huizhi Wang, M.D., Ph.D., assistant professor of oral immunology and infectious diseases at the UofL School of Dentistry. “These data, if confirmed, indicate that eradication of a common oral pathogen may contribute to a reduction in the significant number of people suffering with ESCC.”

The esophagus, a muscular tube critical to the movement of food from the mouth to the stomach, is lined with two main kinds of cells, thus there are two main types of esophageal cancer: adenocarcinoma and squamous cell carcinoma. The latter is more common in developing countries.

In collaboration with the College of Clinical Medicine of Henan University of Science and Technology in Luoyang, China, Wang and his UofL colleagues Richard J. Lamont, Ph.D., Jan Potempa, Ph.D., D.Sc., and David A. Scott, Ph.D., tested tissue samples from 100 patients with ESCC and 30 normal controls.”

To read more about the findings from the research team at UofL School of Dentistry, click here.

 

The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) non profit organization as recognized by the Internal Revenue Service.

Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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‘Jumping genes’ may drive esophageal cancer, Cancer Research UK

July 10, 2015

“Cancer Research UK scientists have found that ‘jumping genes’ may add to the genetic chaos behind more than three-quarters of esophageal cancer cases, according to research published in BMC Genomics.

The scientists, from the University of Cambridge, used cutting-edge technology that can read DNA to study the genes of 43 esophageal tumour and blood samples to discover how much these mobile genetic sequences travel.

‘Jumping genes’, called L1 elements, can uproot themselves and move to new areas in the DNA, sometimes accidentally moving into genes that control the cell’s growth.

They found evidence that this happened around 100 times in each tumour sample, and in some tumours it happened 700 times.

If a jumping gene lands in or near an important gene that controls cell growth, it can wreak havoc, changing how the gene works so that it inadvertently tells the cell to grow and divide out of control – which could lead to cancer.

Study author Dr Paul Edwards, at the Cancer Research UK Cambridge Institute, said: “These jumping genes play hopscotch across our genetic code in cancer cells more than in normal cells. When one of these mobile genetic sequences plants itself in the middle of a gene that controls the cell’s growth it radically alters how the cell behaves, which can sometimes cause cancer.

“Research has shown that this might also happen in lung and bowel cancers. So it’s vital we find out more about how the cells do this in a bid to find ways to treat these cancers.”

The research is part of the International Cancer Genome Consortium (ICGC) – a global project using the latest gene sequencing technology to reveal the genetic changes behind cancer.  The esophageal cancer project is funded by Cancer Research UK.

Dr Kat Arney, Cancer Research UK’s science information manager, said: “Esophageal cancer is one of the hardest cancers to treat, and we are committed to funding more research to find out its underlying causes. These new findings reveal more about the genetic chaos that underpins esophageal tumours, and could one day help us develop better ways to diagnose, treat and monitor the disease.”

References: Paterson et al. Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired end sequencing analysis. BMC Genomics. DOI: 10.1186/s12864-015-1685-z.

This post is based on materials provided by Cancer Research UK.

 

 

The Salgi Esophageal Cancer Research Foundation is a 501 (c) (3) non profit organization as recognized by the Internal Revenue Service.

Content found on Salgi.org is for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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